Biosensors/Implant Devices
Biological Functionalisation of Surfaces
Surface characteristics can play a pivotal role in modulating the behaviour of cellular systems. Understanding the complex way in which they can direct cell growth, migration and differentiation is important in developing new and next generation medical implant devices.
INEX has experience in the following:
- Chemical modification of substrates to prevent/encourage cell adhesion.
- Use of biomolecules such as collagen, laminin and poly-lysine to encourage cell adhesion.
- Creation of topographical features. Three dimensional structures can be used to direct cell growth and migration.
Glass substrate modified with collagen.
Differentiated PC12 cells adhere to the printed biomolecule and growth is directed along the permissive pathway. (Scale bar 100 µm)
Differentiated PC12 cells adhere to the printed biomolecule and growth is directed along the permissive pathway. (Scale bar 100 µm)